Searchable abstracts of presentations at key conferences in endocrinology

ea0063p34 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Aldosterone measurement in the Diagnosis of primary aldosteronism – comparison between two automated immunoassays and two liquid chromatography tandem mass-spectrometry methods

Fagotto Valentina , Uhl Olaf , Heinrich Daniel , Nirschl Nina , Sturm Lisa , Kratzsch Jurgen , Bae Yoon Ju , Fries Charlotte , Fenske Wiebke , Reincke Martin , Bidlingmaier Martin

Poor agreement between different analytical methods measuring aldosterone concentrations impedes applicability of uniform cut-offs in the diagnostic work-up of primary aldosteronism (PA). We compared 4 analytical methods (2 immunoassays and 2 LC-MS/MS) in plasma samples before and after saline infusion test (SIT). 80 hypertensive patients underwent the standardized diagnostic work-up within the German Conn’s registry. Patients (PA n=39/non-PA n=41) were ...